- Circadian and Cincinnati Children’s Hospital Medical Center (“Cincinnati Children’s”) commences offering of first blood test diagnostic for LAM – a serious lung disease that is often undiagnosed.
- Number of tests expected to exceed 25,000 within the next few years.
Circadian Technologies
(ASX:CIR) has announced today that in conjunction with Cincinnati Children’s Hospital Medical Center it has begun offering its LAM diagnostic, which is offered as a laboratory test compliant with CAP (College of American Pathologists) /CLIA regulations.
This is the first blood based diagnostic available to test for the disease lymphangioleiomyomatosis (LAM). The blood sample based diagnostic was developed by Cincinnati Children’s, using Circadian’s VEGF-D technology, following the discovery that high levels of vascular endothelial growth factor-D, or VEGF-D – to which Circadian owns intellectual property rights – holds the key to detecting the disease.
LAM is a serious lung disease that causes shortness of breath and lung collapse. It affects mostly women, often striking in their 30s or child bearing years, and the only known treatment is a lung transplant.
Although only a small number of patients have been diagnosed with LAM to date, the recent discovery of a link between LAM and genetic abnormality, Tuberous Sclerosis Complex (TSC), causing the disease, has led scientists to estimate that more than 250,000 women worldwide are unaware they have LAM.
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