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Chimeric Therapeutics - Quarterly Activities/Appendix 4C Cash Flow Report

Chimeric Therapeutics (ASX:CHM, “Chimeric” or the “Company”), the ASX leader in cell therapy, is pleased to provide a summary of its activities for the quarter ended 31 December 2021.

Key highlights for the quarter included:

  • Exclusive option to licence transformative CORE-NK platform obtained, enabling the accelerated development of multiple next generation NK and CAR-NK products
  • Four new Chimeric assets to initiate development beginning in 2022, leveraging the company’s existing portfolio of CARs
  • Initial positive phase 1 clinical data presented for lowest dose level (44 X 106 CLTX CAR T cells), with therapy generally well tolerated and a 75% disease control rate for up to 8 weeks
  • Completion of CLTX CAR T dose level 2 with no dose limiting toxicities ; dose level 3 enrollment open
  • Manufacturing for CHM 2101 research grade plasmids successfully completed, a critical first step in the development of CDH17 CAR T
  • Dr Eliot Bourk promoted to role of Chief Business Officer (CBO) and Head of External Innovation
For more information, download the attached PDF.

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