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Imugene Announces Novel Anti-PD-1 Mimotope Vaccine Ready for Development

- Paradigm shift in treatment utilises a patient’s B cells to produce antibodies against regulatory check-point targets

- Vaccine mimics check-point inhibitors – a multi billion-dollar drug class

- Broad platform patent filed to protect method of treatment

MELBOURNE Australia 12 February, 2018: Imugene Limited (ASX:IMU), a clinical-stage immuno-oncology company, announces completion of early development of a new mimotope vaccine that will target and compete in the billion-dollar blockbuster anti-PD-1 immuno-oncology market. This announcement follows 18 months of intensive research conducted in partnership with the Medical University of Vienna.

A mimotope induces an antibody reaction against a target, in this case, a regulatory immune check-point known as PD-1. Mimotope induced antibodies may have advantages over synthetic antibodies including, safety, longer responses, memory and cost.

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