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Imugene Announces Endpoints Met in Phase 1b Gastric Cancer Immuno-oncology Trial

• Safety, tolerability & phase 2 dose determined

• Phase 2 trial first patient to be dosed early 2019

• 5 patients with partial responses

• 4 patients with stable disease

SYDNEY, Australia, 17 December 2018: Imugene Limited (ASX:IMU), a clinical stage immuno-oncology company, today announced meeting study endpoints and positive top-line results from the Phase 1b study of its HER-Vaxx gastric cancer vaccine in patients expressing the HER2 target protein.

The 14 patient study tested three dose levels of HER-Vaxx (10, 30 and 50 micrograms) in combination with current standard of care chemotherapy, cisplatin and fluorouracil or capecitabine. All dose levels showed an increased antibody response in patients.

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